Health Minister Ong Ye Kung on Friday (Jan 7) said that it was "too early" to determine if further doses of the COVID-19 vaccine would be required.
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In a Facebook post, Mr Ong answered a series of FAQs following the multi-ministry task force press conference earlier this week.
One of the queries asked: "Now that we must get a third dose to get our vaccination status extended, does that mean there will be a fourth, fifth, sixth dose?"
Mr Ong stated that Israel is the only country so far to administer a fourth dose for people who are not immunocompromised.
"It is too early to answer that question. If we look at an endemic disease like Influenza, people take annual vaccines to protect themselves. This is because the Influenza virus keeps mutating so a new vaccine dose is necessary every year," he said.
"So whether we need future COVID-19 vaccine doses, depends on how fast the protection from three doses wanes, and whether the virus keeps mutating."
Israeli Prime Minister Naftali Bennett on Tuesday announced that a fourth dose of COVID-19 vaccine boosts antibodies five-fold a week after the shot is administered. The country is now administering fourth doses of the Pfizer-BioNTech vaccine to people over 60, health workers and immunocompromised patients.